Gene

gpsm2

ID

ZDB-GENE-040426-1169

Name

G protein signaling modulator 2

Symbol

gpsm2 Nomenclature History

Previous Names

zgc:63574

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to enable G-protein alpha-subunit binding activity and GDP-dissociation inhibitor activity. Predicted to be involved in establishment of mitotic spindle orientation. Predicted to be located in plasma membrane. Predicted to be active in cell cortex. Human ortholog(s) of this gene implicated in sensorineural hearing loss. Orthologous to human GPSM2 (G protein signaling modulator 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gpsm2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Chudley-McCullough syndrome	604213

Associated With gpsm2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003109	GoLoco motif
Family	IPR052386	G-protein-signaling modulator
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR019734	Tetratricopeptide repeat

Domain Details Per Protein

Protein	Length	GoLoco motif	G-protein-signaling modulator	Tetratricopeptide-like helical domain superfamily	Tetratricopeptide repeat
UniProtKB:A0A8M2BJ54 InterPro	667
UniProtKB:A0A8M9Q675 InterPro	670
UniProtKB:F1QUW2 InterPro	649
UniProtKB:Q7SYC6 InterPro	649

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gpsm2-201 (1) Ensembl	Ensembl	2,884 nt	Select Tool ZFIN BLAST
mRNA	gpsm2-202 (1) Ensembl	Ensembl	2,302 nt	Select Tool ZFIN BLAST
mRNA	gpsm2-203 (1) Ensembl	Ensembl	500 nt	Select Tool ZFIN BLAST
mRNA	gpsm2-205 (1) Ensembl	Ensembl	928 nt	Select Tool ZFIN BLAST
ncRNA	gpsm2-004 (1) Ensembl	Ensembl	781 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations