ZFIN ID: ZDB-GENE-030925-47

Gene Name:par-3 partitioning defective 3 homolog (C. elegans)
Gene Symbol: pard3

Previous Names: par-3, ASIP(1) , asip, par3, bazooka
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	2 figure(s) from 2 publications
Directly submitted expression data:	1 figure(s) (1 images) from Thisse et al., 2005 [eu393]
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Hatching:Pec-fin (60.00h-72.00h)
	whole organism
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   2 genotypes
Allele(s):   fh305, unrec_pard3

Phenotype: (current status)

Data:	4 figures from 2 publications
Observed in:	brain, centrosome, cilium axoneme, eye, neural rod ... (all 6)

Knockdown reagents: MO1-pard3 (1) ,   MO2-pard3 (1) ,   MO3-pard3 (1) ,   MO4-pard3 (1) ,   MO5-pard3 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	camera-type eye development (more)
Cellular Component	apical plasma membrane (more)
Molecular Function	protein binding

All GO Terms (8)

Protein Families, Domains and Sites:

InterPro:IPR001478 (1) InterPro:IPR021922 (1)

PROSITE:PS50106 (1)

Pfam:PF00595 (1) Pfam:PF12053 (1)

Gene Product Description

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ANTIBODIES:

Ab1-pard3 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

pard3 Contained in	[BAC] CH211-212E22 (1)    (order this) , DKEY-218A22 (1)    (order this)
pard3 Encodes	[EST] eu393 (1) [cDNA] MGC:193552 (1)    (order this) , MGC:193558 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_205735 (1)	3855 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX088727 (1)	185178 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q6QUY2 (1)	1332 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:26612 (1)
All Sequence Information (21)

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OTHER  pard3  GENE / MARKER PAGES:

Entrez Gene:403050 (1)

VEGA:OTTDARG00000019990 (1)

Ensembl(Zv8):ENSDARG00000010583 (1)

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MAPPING INFORMATION:

LG:  2    Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA
Zebrafish	pard3	2
Human	PARD3	10 (p11.21)	OMIM:606745 Entrez Gene:56288
Orthology Details

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CITATIONS   (18)