Research
General Information
ZIRC
ZFIN: Gene: pard3
ZFIN ID: ZDB-GENE-030925-47

Gene Name:par-3 partitioning defective 3 homolog (C. elegans)
Gene Symbol: pard3
Previous Names: par-3, ASIP(1) , asip, par3, bazooka
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 2 figure(s) from 2 publications
Directly submitted expression data: 1 figure(s) (1 images) from Thisse et al., 2005 [eu393]
Wild Type Stages, Structures: Zygote:1-cell (0.00h-0.75h) to Hatching:Pec-fin (60.00h-72.00h)
  whole organism
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   2 genotypes
Allele(s):   fh305, unrec_pard3
Phenotype: (current status)
  Data: 4 figures from 2 publications
  Observed in: brain, centrosome, cilium axoneme, eye, neural rod ... (all 6)
Knockdown reagents: MO1-pard3 (1) ,   MO2-pard3 (1) ,   MO3-pard3 (1) ,   MO4-pard3 (1) ,   MO5-pard3 (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process camera-type eye development (more)
Cellular Component apical plasma membrane (more)
Molecular Function protein binding
All GO Terms (8)

Protein Families, Domains and Sites:
  • InterPro:IPR001478 (1)
  • InterPro:IPR021922 (1)
  • PROSITE:PS50106 (1)
  • Pfam:PF00595 (1)
  • Pfam:PF12053 (1)
  • Loading Transcript Data...

    Gene Product Description


    ANTIBODIES:
    Ab1-pard3 (1)


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    pard3 Contained in [BAC] CH211-212E22 (1)    (order this) , DKEY-218A22 (1)    (order this)
    pard3 Encodes [EST] eu393 (1)
    [cDNA] MGC:193552 (1)    (order this) , MGC:193558 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205735 (1) 3855 bp
    Genomic GenBank:BX088727 (1) 185178 bp
    Polypeptide UniProtKB:Q6QUY2 (1) 1332 aa
    Sequence Clusters UniGene:26612 (1)
    All Sequence Information (21)

    OTHER  pard3  GENE / MARKER PAGES:

  • Entrez Gene:403050 (1)
  • VEGA:OTTDARG00000019990 (1)
  • Ensembl(Zv8):ENSDARG00000010583 (1)

  • MAPPING INFORMATION:
      LG:  2    Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish pard3  2
    Human PARD3  10 (p11.21)
  • OMIM:606745
  • Entrez Gene:56288
  • Orthology Details

    CITATIONS   (18)