ZFIN is now using GRCz12tu for Genomic Data
Gene
oprk1
- ID
- ZDB-GENE-030729-1
- Name
- opioid receptor, kappa 1
- Symbol
- oprk1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables peptide binding activity. Predicted to be involved in G protein-coupled opioid receptor signaling pathway. Predicted to be located in plasma membrane. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; drug dependence (multiple); neonatal abstinence syndrome; and opioid abuse. Orthologous to human OPRK1 (opioid receptor kappa 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Depienne et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Opioid receptor |
|---|---|---|---|---|---|
| UniProtKB:Q98U14 | InterPro | 377 | |||
| UniProtKB:A0A8M2BAU5 | InterPro | 434 | |||
| UniProtKB:A0A8M1P7D3 | InterPro | 404 | |||
| UniProtKB:B3DGN0 | InterPro | 377 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers