Gene
triob
- ID
- ZDB-GENE-030616-399
- Name
- trio Rho guanine nucleotide exchange factor b
- Symbol
- triob Nomenclature History
- Previous Names
-
- trio
- si:dz230d15.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; Rho guanyl-nucleotide exchange factor activity; and protein kinase activity. Predicted to be involved in axon guidance; central nervous system development; and protein phosphorylation. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability and autosomal dominant non-syndromic intellectual disability 44. Orthologous to human TRIO (trio Rho guanine nucleotide exchange factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1114 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 44 | Alliance | Intellectual developmental disorder, autosomal dominant 44, with microcephaly | 617061 |
| Intellectual developmental disorder, autosomal dominant 63, with macrocephaly | 618825 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | ottdart00000001996 (1) | Havana | 2,271 nt |
Interactions and Pathways
No data available
Plasmids
No data available