ZFIN ID: ZDB-GENE-030616-132

Gene Name:MYC binding protein 2
Gene Symbol: mycbp2

Previous Names: xx:zft368, si:dz12g7.1, si:busm1-12g7.1, PAM(1) , esrom(2) , wu:fa97c06, ns:zft368, tilsit, til, fa97c06, si:dz256p4.1, zft368, esr
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	3 figure(s) from 3 publications
Wild Type Stages, Structures:	Cleavage:4-cell (1.00h-1.25h) to Adult (90d-730d, breeding adult)
	brain, eye ... (all 11)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   19 genotypes
Allele(s):   tb241a, te250, te275, te279, te376 ... (all 18)

Phenotype: (current status)

Data:	17 figures from 2 publications
Observed in:	habenular commissure, nervous system, pigment cell, retinal ganglion cell axon guidance, whole organism ... (all 6)

Knockdown reagents: MO1-mycbp2 (1) ,   MO2-mycbp2 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	axon choice point recognition (more)
Cellular Component	cytoplasm (more)
Molecular Function	ubiquitin-protein ligase activity (more)

All GO Terms (12)

Protein Families, Domains and Sites:

InterPro:IPR000408 (1) InterPro:IPR001841 (1) InterPro:IPR004939 (1) InterPro:IPR008979 (1) InterPro:IPR009091 (1) InterPro:IPR012983 (1) InterPro:IPR014756 (1) InterPro:IPR017868 (1)

PROSITE:PS00626 (1) PROSITE:PS50012 (1) PROSITE:PS50089 (1) PROSITE:PS50194 (1) PROSITE:PS51284 (1)

Pfam:PF00415 (1) Pfam:PF00630 (1) Pfam:PF08005 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

mycbp2 Contained in	[BAC] CH211-4P8 (1)    (order this) , CH211-221B16 (1)    (order this) , CH211-279B21 (1)    (order this) , DKEY-250A21 (1)    (order this) [PAC] BUSM1-12G7 (1)    (order this) , BUSM1-256P4    (order this)
mycbp2 Encodes	[EST] fa97c06 , zft368

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001012247 (1)	15334 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX510646 (1)	200321 bp	- Select Tool - MegaBLAST
Polypeptide	UniProtKB:Q5IBM5 (1)	4574 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:146702 (1)
All Sequence Information (26)

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OTHER  mycbp2  GENE / MARKER PAGES:

Entrez Gene:368439 (1)

VEGA:OTTDARG00000001756 (1) VEGA:OTTDARG00000001868 (1) VEGA:OTTDARG00000030613 (1)

Ensembl(Zv8):ENSDARG00000001220 (1)

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MAPPING INFORMATION:

LG:  2 ,  9    Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	mycbp2	2 ,  9
Human	MYCBP2	13 (q22)	Entrez Gene:23077
Mouse	Mycbp2	14 (54.58 cM)	MGI:2179432 Entrez Gene:105689
Orthology Details

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CITATIONS   (26)