Gene
cdkn1bb
- ID
- ZDB-GENE-030521-13
- Name
- cyclin dependent kinase inhibitor 1Bb
- Symbol
- cdkn1bb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have chaperone binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to be involved in G1/S transition of mitotic cell cycle; negative regulation of cell cycle; and negative regulation of cell population proliferation. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; breast cancer; multiple endocrine neoplasia type 4; and myelodysplastic syndrome. Is expressed in several structures, including axis; nervous system; pectoral fin; polster; and solid lens vesicle. Orthologous to human CDKN1B (cyclin dependent kinase inhibitor 1B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 34 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb611 (12 images)
- IMAGE:7152670 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| multiple endocrine neoplasia type 4 | Alliance | Multiple endocrine neoplasia, type IV | 610755 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin-dependent kinase inhibitor domain | Cyclin-dependent kinase inhibitor domain superfamily |
|---|---|---|---|
|
UniProtKB:Q90YX4
|
179 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdkn1bb-201
(1)
|
Ensembl | 1,921 nt | ||
| ncRNA |
cdkn1bb-002
(1)
|
Ensembl | 864 nt |
Interactions and Pathways
No data available
Plasmids
No data available