Research
General Information
ZIRC
ZFIN: Gene: gli1
ZFIN ID: ZDB-GENE-030321-1

Gene Name:GLI-Kruppel family member 1
Gene Symbol: gli1
Previous Names: detour, dtr


GENE EXPRESSION:(current status)
All expression data: 19 figure(s) from 11 publications
Directly submitted expression data: 6 figure(s) (15 images) from Thisse et al., 2005 [eu934]
Wild Type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.00h-60.00h)
  adaxial cell, adenohypophyseal placode ... (all 29)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   8 genotypes
Allele(s):   te370a, tm276b, ts269, unspecified_gli1
Phenotype: (current status)
  Data: 10 figures from 5 publications
  Observed in: adenohypophyseal placode, adenohypophysis, adenohypophysis morphogenesis, adrenocorticotropic hormone secreting cell, adrenocorticotropin hormone secreting cell differentiation ... (all 24)
Knockdown reagent: MO1-gli1 (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process floor plate formation (more)
Cellular Component Hedgehog signaling complex (more)
Molecular Function protein binding (more)
All GO Terms (15)

Protein Families, Domains and Sites:
  • InterPro:IPR007087 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR015880 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)

  • SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    gli1 Encodes [EST] eu934 (1)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_178296 (1) 4726 bp
    Genomic GenBank:DU645157 440 bp
    Polypeptide UniProtKB:Q800Z9 (1) 1404 aa
    Sequence Clusters UniGene:88778 (1)
    All Sequence Information (7)

    OTHER  gli1  GENE / MARKER PAGES:

  • Entrez Gene:352930 (1)
  • Ensembl(Zv8):ENSDARG00000033680 (1)

  • MAPPING INFORMATION:
      LG:  6    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA FC
    Zebrafish gli1  6
    Human GLI1  12 (q13.2-q13.3)
  • OMIM:165220
  • Entrez Gene:2735
  • Mouse Gli1  10 (69.00 cM)
  • MGI:95727
  • Entrez Gene:14632
  • Orthology Details

    CITATIONS   (59)