Gene

creb3l1

ID

ZDB-GENE-030219-181

Name

cAMP responsive element binding protein 3-like 1

Symbol

creb3l1 Nomenclature History

Previous Names

fa98d12
id:ibd2573
id:ibd5131
wu:fa98d12

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cAMP response element binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in endoplasmic reticulum membrane and nucleus. Is expressed in axial chorda mesoderm; notochord; shield; and tail bud. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to human CREB3L1 (cAMP responsive element binding protein 3 like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from Kudoh et al., 2001

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With creb3l1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
osteogenesis imperfecta type 16	Alliance	Osteogenesis imperfecta, type XVI	616229

Associated With creb3l1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:E7FCG3	InterPro	526
UniProtKB:A0A8M3AUC8	InterPro	515
UniProtKB:A0A0R4IKX3	InterPro	492
UniProtKB:A0A8M3BB36	InterPro	404

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	creb3l1-201 (1) Ensembl	Ensembl	3,903 nt	Select Tool ZFIN BLAST
mRNA	creb3l1-202 (1) Ensembl	Ensembl	1,479 nt	Select Tool ZFIN BLAST
mRNA	creb3l1-203 (1) Ensembl	Ensembl	452 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations