Gene
capzb
- ID
- ZDB-GENE-030131-7023
- Name
- capping actin protein of muscle Z-line subunit beta
- Symbol
- capzb Nomenclature History
- Previous Names
-
- wu:fk65f06
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Acts upstream of or within muscle cell development and neural crest cell migration. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of F-actin capping protein complex. Is expressed in fin bud; head; pharyngeal arch; and somite. Used to study cleft palate. Orthologous to human CAPZB (capping actin protein of muscle Z-line subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Mukherjee et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| cleft palate | capzbhi1858bTg/hi1858bTg | standard conditions | Mukherjee et al., 2016 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019771 | F-actin capping protein, beta subunit, conserved site |
| Family | IPR001698 | F-actin-capping protein subunit beta |
| Homologous_superfamily | IPR037282 | F-actin-capping protein subunit alpha/beta |
| Homologous_superfamily | IPR042276 | F-actin-capping protein subunit alpha/beta, domain 2 |
| Homologous_superfamily | IPR043175 | F-actin-capping protein subunit beta, N-terminal domain |
Domain Details Per Protein
| Protein | Length | F-actin capping protein, beta subunit, conserved site | F-actin-capping protein subunit alpha/beta | F-actin-capping protein subunit alpha/beta, domain 2 | F-actin-capping protein subunit beta | F-actin-capping protein subunit beta, N-terminal domain |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AUB3
|
274 | |||||
|
UniProtKB:Q7SXP1
|
273 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available