Gene

trmt2a

ID

ZDB-GENE-030131-6876

Name

tRNA methyltransferase 2 homolog A

Symbol

trmt2a Nomenclature History

Previous Names

fa10b06
htf9c (1)
wu:fa10b06
zgc:55519

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have RNA binding activity and RNA methyltransferase activity. Predicted to be involved in RNA processing and methylation. Is expressed in several structures, including cerebellum; digestive system; midbrain; pectoral fin musculature; and retina. Orthologous to human TRMT2A (tRNA methyltransferase 2 homolog A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55519 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trmt2a Human Ortholog

No data available

Associated With trmt2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR030390	RNA methyltransferase TrmA, active site
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034262	TRMT2A, RNA recognition motif
Family	IPR010280	(Uracil-5)-methyltransferase family
Family	IPR045850	tRNA (uracil(54)-C(5))-methyltransferase, metazoa type
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA methyltransferase TrmA, active site	RNA recognition motif domain	S-adenosyl-L-methionine-dependent methyltransferase superfamily	TRMT2A, RNA recognition motif	tRNA (uracil(54)-C(5))-methyltransferase, metazoa type	(Uracil-5)-methyltransferase family
UniProtKB:Q7ZVY1 InterPro	619

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trmt2a-201 (1) Ensembl	Havana	2095 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	trmt2a-002 (1) Ensembl	Havana	732 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations