Gene
ddx46
- ID
- ZDB-GENE-030131-667
- Name
- DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
- Symbol
- ddx46 Nomenclature History
- Previous Names
-
- fb39a03
- fj67d06
- wu:fb39a03 (1)
- wu:fj67d06
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity and RNA helicase activity. Involved in several processes, including animal organ development; mRNA splicing, via spliceosome; and positive regulation of hemopoiesis. Predicted to localize to nucleus. Is expressed in brain; digestive system; head; hematopoietic system; and pectoral fin bud. Orthologous to human DDX46 (DEAD-box helicase 46).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000629 | ATP-dependent RNA helicase DEAD-box, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR014014 | RNA helicase, DEAD-box type, Q motif |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ATP-dependent RNA helicase DEAD-box, conserved site | DEAD/DEAH box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RNA helicase, DEAD-box type, Q motif |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q4TVV3
|
1018 | ||||||
|
UniProtKB:A0A8M3AX96
|
1035 |
Interactions and Pathways
No data available
Plasmids
No data available