Gene

psmc5

ID

ZDB-GENE-030131-6547

Name

proteasome 26S subunit, ATPase 5

Symbol

psmc5 Nomenclature History

Previous Names

wu:fa14g03
wu:fb23a11
zgc:92464

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have TBP-class protein binding activity and thyrotropin-releasing hormone receptor binding activity. Predicted to be involved in modulation of chemical synaptic transmission; positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to postsynapse and proteasome complex. Orthologous to human PSMC5 (proteasome 26S subunit, ATPase 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92464 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With psmc5 Human Ortholog

No data available

Associated With psmc5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003960	ATPase, AAA-type, conserved site
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR032501	Proteasomal ATPase, second OB domain
Domain	IPR041569	AAA ATPase, AAA+ lid domain
Family	IPR050221	26S Proteasome Regulatory ATPase
Homologous_superfamily	IPR012340	Nucleic acid-binding, OB-fold
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase