Gene
cox5ab
- ID
- ZDB-GENE-030131-5162
- Name
- cytochrome c oxidase subunit 5Ab
- Symbol
- cox5ab Nomenclature History
- Previous Names
-
- Cox5a2 (1)
- cox5a
- cb01f09
- mg:cb01f09
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Enables cytochrome-c oxidase activity. Acts upstream of or within embryonic organ development; proton transmembrane transport; and spinal cord motor neuron differentiation. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 20. Orthologous to human COX5A (cytochrome c oxidase subunit 5A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Baden et al., 2007
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 20 | Alliance | Mitochondrial complex IV deficiency, nuclear type 20 | 619064 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome c oxidase, subunit Va/VI | Cytochrome c oxidase, subunit Va/VI superfamily |
|---|---|---|---|---|
| UniProtKB:A0A0R4IVC8 | InterPro | 138 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cox5ab-201
(1)
|
Ensembl | 673 nt |
Interactions and Pathways
No data available
Plasmids
No data available