ZFIN ID: ZDB-GENE-030131-4827

Gene Name:hedgehog interacting protein
Gene Symbol: hhip

Previous Names: ukkie, zgc:153478, wu:fd99f01, fd99f01, Hip(1) , uki, wu:fc52e12
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	3 figure(s) from 2 publications
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Hatching:Long-pec (48.00h-60.00h)
	adaxial cell, adductor mandibulae ... (all 17)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   10 genotypes
Allele(s):   hu418b, hu540a, tc256d

Phenotype: (current status)

Data:	11 figures from 6 publications
Observed in:	anal fin, anatomical system, cell proliferation, dorsolateral septum, ear morphogenesis ... (all 22)

Knockdown reagents: MO1-hhip (1) ,   MO2-hhip (1) ,   MO3-hhip (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	negative regulation of muscle organ development (more)
Cellular Component	intrinsic to plasma membrane (more)
Molecular Function	catalytic activity

All GO Terms (8)

Protein Families, Domains and Sites:

InterPro:IPR000742 (1) InterPro:IPR006210 (1) InterPro:IPR011041 (1) InterPro:IPR011042 (1) InterPro:IPR013032 (1) InterPro:IPR018143 (1)

PROSITE:PS00022 (1) PROSITE:PS01186 (1) PROSITE:PS50026 (1)

Pfam:PF03024 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

hhip Contained in	[BAC] CH211-194G2 (1)    (order this)
hhip Contains	[SNP] rs3727539 (1)
hhip Encodes	[EST] fc52e12 , fd99f01 [cDNA] MGC:153478 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001080012 (1)	4587 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX276105 (1)	209486 bp	- Select Tool - MegaBLAST
Polypeptide	UniProtKB:A1A5I0 (1)	693 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:119698 (1)
All Sequence Information (14)

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OTHER  hhip  GENE / MARKER PAGES:

Entrez Gene:326102 (1)

VEGA:OTTDARG00000027132 (1) VEGA:OTTDARG00000029896 (1)

Ensembl(Zv8):ENSDARG00000060397 (1)

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MAPPING INFORMATION:

LG:  1    Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	NT	CL
Zebrafish	hhip	1
Human	HHIP	4 (q28-q32)	OMIM:606178 Entrez Gene:64399
Mouse	Hhip	Unknown	MGI:1341847 Entrez Gene:15245
Orthology Details

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CITATIONS   (28)