Gene
rpl27
- ID
- ZDB-GENE-030131-4343
- Name
- ribosomal protein L27
- Symbol
- rpl27 Nomenclature History
- Previous Names
-
- fc93a08
- wu:fc93a08
- zgc:56171 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of ribosome. Involved in erythrocyte differentiation. Predicted to localize to cytoplasmic side of rough endoplasmic reticulum membrane and cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia. Is expressed in endodermal cell; intestine; liver; and pancreas. Orthologous to human RPL27 (ribosomal protein L27).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56171 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wang et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Diamond-Blackfan anemia 16 | Alliance | ?Diamond-Blackfan anemia 16 | 617408 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018262 | Large ribosomal subunit protein eL27, conserved site |
| Domain | IPR005824 | KOW |
| Domain | IPR041991 | Large ribosomal subunit protein eL27, KOW domain |
| Family | IPR001141 | Large ribosomal subunit protein eL27 |
| Homologous_superfamily | IPR008991 | Translation protein SH3-like domain superfamily |
| Homologous_superfamily | IPR038655 | Large ribosomal subunit protein eL27 superfamily |
Domain Details Per Protein
| Protein | Length | KOW | Large ribosomal subunit protein eL27 | Large ribosomal subunit protein eL27, conserved site | Large ribosomal subunit protein eL27, KOW domain | Large ribosomal subunit protein eL27 superfamily | Translation protein SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZV82
|
136 | ||||||
|
UniProtKB:B2GP62
|
136 |
Interactions and Pathways
No data available
Plasmids
No data available