Gene
pigp
- ID
- ZDB-GENE-030131-4041
- Name
- phosphatidylinositol glycan anchor biosynthesis, class P
- Symbol
- pigp Nomenclature History
- Previous Names
-
- dscr5 (1)
- wu:fc66d08
- zgc:73366
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have phosphatidylinositol N-acetylglucosaminyltransferase activity. Involved in convergent extension involved in axis elongation; regulation of JNK cascade; and regulation of convergent extension involved in gastrulation. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 55. Is expressed in blastomere; central nervous system; and somite. Orthologous to human PIGP (phosphatidylinositol glycan anchor biosynthesis class P).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73366 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Shao et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 55 | Alliance | Developmental and epileptic encephalopathy 55 | 617599 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phosphatidylinositol N-acetylglucosaminyltransferase, GPI19/PIG-P subunit | PIG-P |
|---|---|---|---|
|
UniProtKB:A0A2R8Q1D2
|
127 | ||
|
UniProtKB:A0A8M2BJV2
|
196 |
Interactions and Pathways
No data available
Plasmids
No data available