Gene
cst3
- ID
- ZDB-GENE-030131-373
- Name
- cystatin C (amyloid angiopathy and cerebral hemorrhage)
- Symbol
- cst3 Nomenclature History
- Previous Names
-
- fb51d07
- wu:fb24g06
- wu:fb51d07
- wu:fc55f03
- zgc:136227
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have cysteine-type endopeptidase inhibitor activity. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in CST3-related cerebral amyloid angiopathy and age related macular degeneration 11. Orthologous to human CST3 (cystatin C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| age related macular degeneration 11 | Alliance | {Macular degeneration, age-related, 11} | 611953 |
| CST3-related cerebral amyloid angiopathy | Alliance | Cerebral amyloid angiopathy | 105150 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystatin domain | Cystatin superfamily | Proteinase inhibitor I25, cystatin, conserved site |
|---|---|---|---|---|
|
UniProtKB:B8A4C9
|
128 |
Interactions and Pathways
No data available
Plasmids
No data available