Gene

dlg5a

ID

ZDB-GENE-030131-3149

Name

discs, large homolog 5a (Drosophila)

Symbol

dlg5a Nomenclature History

Previous Names

dlg5 (1)
wu:fc28f03

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to be involved in regulation of apoptotic process. Orthologous to human DLG5 (discs large MAGUK scaffold protein 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dlg5a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Yuksel-Vogel-Bauser syndrome	620703

Associated With dlg5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001315	CARD domain
Domain	IPR001452	SH3 domain
Domain	IPR001478	PDZ domain
Domain	IPR006907	Disks large homolog 5, N-terminal
Domain	IPR008144	Guanylate kinase-like domain
Domain	IPR008145	Guanylate kinase/L-type calcium channel beta subunit
Domain	IPR035537	Disks large homologue 5, SH3 domain
Family	IPR053004	MAGUK Family Regulators of Signaling Pathways
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036028	SH3-like domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	CARD domain	Death-like domain superfamily	Disks large homolog 5, N-terminal	Disks large homologue 5, SH3 domain	Guanylate kinase-like domain	Guanylate kinase/L-type calcium channel beta subunit	MAGUK Family Regulators of Signaling Pathways	PDZ domain	PDZ superfamily	P-loop containing nucleoside triphosphate hydrolase	SH3 domain	SH3-like domain superfamily
UniProtKB:A0A8M3BEL3 InterPro	1957
UniProtKB:A0A8M2B3K9 InterPro	1961
UniProtKB:B7ZC95 InterPro	1926
UniProtKB:E7EXQ0 InterPro	1958
UniProtKB:A0A8M9QJT2 InterPro	1413