ZFIN ID: ZDB-GENE-030131-2862

Gene Name:a disintegrin and metalloproteinase domain 17a
Gene Symbol: adam17a

Previous Names: fc20b01, wu:fc20b01, zgc:63886
Nomenclature History

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GENE EXPRESSION:(current status)

Curated microarray expression:

GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Phenotype: (current status)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	integrin-mediated signaling pathway (more)
Molecular Function	hydrolase activity (more)

All GO Terms (8)

Protein Families, Domains and Sites:

InterPro:IPR001590 (1) InterPro:IPR001762 (1) InterPro:IPR002870 (1)

PROSITE:PS50214 (1) PROSITE:PS50215 (1)

Pfam:PF00200 (1) Pfam:PF01421 (1) Pfam:PF01562 (1)

Gene Product Description

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

adam17a Contained in	[BAC] DKEY-174C12 (1)    (order this)
adam17a Encodes	[EST] fc20b01 [cDNA] MGC:63886 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_199673 (1)	5431 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR556709 (1)	73449 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:Q5RFV3 (1)	842 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:59760 (1)
All Sequence Information (11)

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OTHER  adam17a  GENE / MARKER PAGES:

Entrez Gene:324142 (1)

VEGA:OTTDARG00000010942 (1)

Ensembl(Zv8):ENSDARG00000043213 (1)

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MAPPING INFORMATION:

LG:  17  Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	adam17a	17
Human	ADAM17	2 (p25)	OMIM:603639 Entrez Gene:6868
Mouse	Adam17	Unknown	MGI:1096335 Entrez Gene:11491
Orthology Details

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CITATIONS   (12)