Gene

isg15

ID
ZDB-GENE-021211-1
Name
ISG15 ubiquitin like modifier
Symbol
isg15 Nomenclature History
Previous Names
  • g1p2 (1)
  • zfISG15 (1)
  • si:rp71-1c23.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have protein tag and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human ISG15 (ISG15 ubiquitin like modifier).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With isg15 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 38 Alliance Immunodeficiency 38 616126
Associated With isg15 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000626 Ubiquitin-like domain
Domain IPR019956 Ubiquitin domain
Family IPR050158 Ubiquitin and ubiquitin-like
Homologous_superfamily IPR029071 Ubiquitin-like domain superfamily
Domain Details Per Protein
Protein Length Ubiquitin and ubiquitin-like Ubiquitin domain Ubiquitin-like domain Ubiquitin-like domain superfamily
UniProtKB:A2BHB8 157
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations