Gene
mycn
- ID
- ZDB-GENE-020711-1
- Name
- MYCN proto-oncogene, bHLH transcription factor
- Symbol
- mycn Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity; DNA-binding transcription factor activity; and protein dimerization activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Feingold syndrome. Is expressed in several structures, including immature eye; nervous system; pectoral fin bud; pharyngeal arch; and pronephric duct. Orthologous to human MYCN (MYCN proto-oncogene, bHLH transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Feingold syndrome | Alliance | Feingold syndrome 1 | 164280 |
| Megalencephaly-polydactyly syndrome | 620748 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Transcription regulator Myc | Transcription regulator Myc, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q9PSJ0
|
|||||
|
UniProtKB:Q5GFD4
|
456 |
Interactions and Pathways
No data available
Plasmids
No data available