Gene

tnfsf10l

ID
ZDB-GENE-010801-1
Name
TNF superfamily member 10, like
Symbol
tnfsf10l Nomenclature History
Previous Names
  • DL1a (1)
  • TNFSF10-2 (1)
  • TRAIL-like (1)
  • wu:fc12f06
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have metal ion binding activity and tumor necrosis factor receptor binding activity. Involved in positive regulation of extrinsic apoptotic signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Is expressed in several structures, including adaxial cell; central nervous system; endoderm; germ ring; and head. Orthologous to human TNFSF10 (TNF superfamily member 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tnfsf10l Human Ortholog
No data available
Associated With tnfsf10l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006052 Tumour necrosis factor domain
Family IPR017355 Tumour necrosis factor ligand 10/11
Homologous_superfamily IPR008983 Tumour necrosis factor-like domain superfamily
Domain Details Per Protein
Protein Length Tumour necrosis factor domain Tumour necrosis factor ligand 10/11 Tumour necrosis factor-like domain superfamily
UniProtKB:Q7ZYX9 317
UniProtKB:A0A8M2BK35 316
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations