ZFIN is now using GRCz12tu for Genomic Data
Gene
oprm1
- ID
- ZDB-GENE-010125-1
- Name
- opioid receptor, mu 1
- Symbol
- oprm1 Nomenclature History
- Previous Names
-
- ZfMOR (1)
- ZFOR2
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables G protein-coupled enkephalin receptor activity and morphine receptor activity. Predicted to be involved in G protein-coupled opioid receptor signaling pathway; neuropeptide signaling pathway; and sensory perception of pain. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in several structures, including nervous system; notochord; otic vesicle; prechordal plate; and trunk. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; drug dependence (multiple); drug psychosis; and withdrawal disorder (multiple). Orthologous to human OPRM1 (opioid receptor mu 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Mu opioid receptor | Opioid receptor |
|---|---|---|---|---|---|---|
| UniProtKB:B8JHS2 | InterPro | 382 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers