ZFIN is now using GRCz12tu for Genomic Data
Gene
bfb
- ID
- ZDB-GENE-990415-34
- Name
- complement component bfb
- Symbol
- bfb Nomenclature History
- Previous Names
-
- Bf-2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in immune response and response to bacterium. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; eye disease (multiple); glomerulonephritis (multiple); sickle cell anemia; and type 1 diabetes mellitus. Orthologous to human CFB (complement factor B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92519 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily | von Willebrand factor A-like domain superfamily | von Willebrand factor, type A |
|---|---|---|---|---|---|---|
| UniProtKB:Q6DHC4 | InterPro | 456 | ||||
| UniProtKB:A0A8M9PTN0 | InterPro | 448 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers