ZFIN is now using GRCz12tu for Genomic Data

Gene

elavl4

ID

ZDB-GENE-990415-246

Name

ELAV like neuron-specific RNA binding protein 4

Symbol

elavl4 Nomenclature History

Previous Names

elrd (1)
elav-related D
wu:fc24h01
zHuD (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable mRNA 3'-UTR AU-rich region binding activity and protein-RNA adaptor activity. Acts upstream of or within axonogenesis. Predicted to be located in cytoplasm and perikaryon. Predicted to be part of ribonucleoprotein complex. Predicted to be active in axon. Is expressed in heart; nervous system; swim bladder; and trigeminal placode. Orthologous to human ELAVL4 (ELAV like RNA binding protein 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

22 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77361 (12 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 6 figures from Hao et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With elavl4 Human Ortholog

No data available

Associated With elavl4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034918	HuD, RNA recognition motif 3
Family	IPR002343	Paraneoplastic encephalomyelitis antigen
Family	IPR006548	Splicing factor ELAV/Hu
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:F1QGR7	InterPro	403
UniProtKB:A0A8M6Z808	InterPro	369
UniProtKB:A0A8M9QIF9	InterPro	395
UniProtKB:A0A8M9Q9I0	InterPro	398
UniProtKB:A0A0R4IEW8	InterPro	411
UniProtKB:A0A8M2BEA7	InterPro	382
UniProtKB:A0A8M9Q398	InterPro	408
UniProtKB:A0AB32TT42	InterPro	411
UniProtKB:A0AB32TU00	InterPro	369
UniProtKB:A0AB32TUE3	InterPro	374
UniProtKB:A0AB32TWH2	InterPro	398
UniProtKB:A0AB32TY95	InterPro	382
UniProtKB:A0AB32TYV7	InterPro	441
UniProtKB:A0AB32TZW3	InterPro	454
UniProtKB:A0AB32TZW9	InterPro	438
UniProtKB:A0AB32U130	InterPro	451
UniProtKB:A0AC58G643	InterPro	395
UniProtKB:A0AC58G647	InterPro	408
UniProtKB:A0AC58G650	InterPro	382
UniProtKB:A0AC58G651	InterPro	395
UniProtKB:A0AC58G653	InterPro	400
UniProtKB:A0AC58G655	InterPro	371
UniProtKB:A0AC58G656	InterPro	358
UniProtKB:A0AC58G657	InterPro	379
UniProtKB:A0AC58G658	InterPro	366
UniProtKB:A0AC58G665	InterPro	366
UniProtKB:A0AC58G668	InterPro	387
UniProtKB:A0AC58G6A1	InterPro	353

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	elavl4-201 (1) Ensembl	Ensembl	2,109 nt	Select Tool ZFIN BLAST
mRNA	elavl4-202 (1) Ensembl	Ensembl	1,818 nt	Select Tool ZFIN BLAST
mRNA	elavl4-203 (1) Ensembl	Ensembl	797 nt	Select Tool ZFIN BLAST
mRNA	elavl4-205 (1) Ensembl	Ensembl	6,093 nt	Select Tool ZFIN BLAST
mRNA	elavl4-206 (1) Ensembl	Ensembl	5,416 nt	Select Tool ZFIN BLAST
ncRNA	elavl4-006 (1) Ensembl	Ensembl	1,293 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-elavl	monoclonal	elavl3 elavl4	IgG2b	Mouse	IHC	Santa Cruz Biotechnology, Inc. Life Technologies (Invitrogen) Abcam plc MoBiTec Molecular Biotechnology Molecular Probes, Inc.	529

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations