Gene
casp21
- ID
- ZDB-GENE-190425-1
- Name
- caspase 21, apoptosis-related cysteine peptidase
- Symbol
- casp21 Nomenclature History
- Previous Names
-
- casp7l (1)
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Is expressed in cranial blood vessel; intestinal bulb; muscle cell; nervous system; and pharyngeal arch. Orthologous to human CASP3 (caspase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Spead et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016129 | Peptidase family C14A, His active site |
| Active_site | IPR033139 | Peptidase family C14A, cysteine active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Caspase-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, cysteine active site | Peptidase family C14A, His active site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F386
|
266 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available