Gene

si:dkey-10b15.8

ID
ZDB-GENE-141212-238
Name
si:dkey-10b15.8
Symbol
si:dkey-10b15.8 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 8; Parkinson's disease; and motor neuron disease. Orthologous to human HTRA2 (HtrA serine peptidase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:dkey-10b15.8 Human Ortholog
No data available
Associated With si:dkey-10b15.8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR041489 PDZ domain 6
Family IPR001940 Peptidase S1C
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length PDZ domain PDZ domain 6 PDZ superfamily Peptidase S1C Peptidase S1, PA clan
UniProtKB:F1Q918 214
UniProtKB:A0A8M9PLU9 215
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA si:dkey-10b15.8-001 (1) Havana 1254 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations