Gene

prkd3

ID

ZDB-GENE-130530-880

Name

protein kinase D3

Symbol

prkd3 Nomenclature History

Previous Names

zmp:0000000877 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. Orthologous to human PRKD3 (protein kinase D3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prkd3 Human Ortholog

No data available

Associated With prkd3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR020454	Diacylglycerol/phorbol-ester binding
Family	IPR015727	Protein kinase C mu-related
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	C1-like domain superfamily	Diacylglycerol/phorbol-ester binding	PH-like domain superfamily	Pleckstrin homology domain	Protein kinase, ATP binding site	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Protein kinase C mu-related	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:E7F9Z2 InterPro	891
UniProtKB:A0A8M3B2L1 InterPro	890
UniProtKB:A0A8M9PLK0 InterPro	634

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	prkd3-201 (1) Ensembl	Ensembl		4,617 nt	Select Tool ZFIN BLAST
mRNA	prkd3-202 (1) Ensembl	Ensembl		7,875 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations