Gene

lrrc7

ID

ZDB-GENE-130530-876

Name

leucine rich repeat containing 7

Symbol

lrrc7 Nomenclature History

Previous Names

zmp:0000000873 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable protein kinase binding activity. Predicted to be involved in cell-cell adhesion; establishment or maintenance of epithelial cell apical/basal polarity; and protein localization to membrane. Predicted to be active in adherens junction; basolateral plasma membrane; and postsynaptic density. Predicted to colocalize with postsynaptic membrane. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human LRRC7 (leucine rich repeat containing 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrrc7 Human Ortholog

No data available

Associated With lrrc7 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001478	PDZ domain
Family	IPR050614	Synaptic Scaffolding LAP/MAGUK Families
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Length	Leucine-rich repeat	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype	PDZ domain	PDZ superfamily	Synaptic Scaffolding LAP/MAGUK Families
UniProtKB:A0A8M3BAF2 InterPro	1500
UniProtKB:A0A8M2BDE2 InterPro	1548
UniProtKB:A0A8M3ATF9 InterPro	1499
UniProtKB:A0A8M2BDA7 InterPro	1554
UniProtKB:A0A8M3B0I0 InterPro	1537
UniProtKB:A0A8M2BDI3 InterPro	1506
UniProtKB:A0A8M2BDH3 InterPro	1556
UniProtKB:A0A8M2BDC0 InterPro	1527
UniProtKB:A0A8M2BDA8 InterPro	1550

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	lrrc7-201 (1) Ensembl	Ensembl		4,338 nt	Select Tool ZFIN BLAST
mRNA	lrrc7-202 (1) Ensembl	Ensembl		4,945 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations