Gene
shtn2
- ID
- ZDB-GENE-130530-561
- Name
- shootin 2
- Symbol
- shtn2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to be involved in neuron projection morphogenesis and positive regulation of neuron migration. Predicted to be active in axonal growth cone; cell leading edge; and cytoplasm.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Urasaki et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa9626 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa15465 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa20861 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa26885 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa26886 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| syu204 | Allele with one deletion | Exon 4 | Unknown | CRISPR |
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| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-shtn2 | Zebrafish Nomenclature Committee |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR024849 | Shootin-1 |
1 - 1 of 1
Domain Details Per Protein
| Protein | Length | Shootin-1 |
|---|---|---|
|
UniProtKB:F1R1Q1
|
561 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-1o7.3-201
(1)
|
Ensembl | 1,946 nt | ||
| mRNA |
si:ch211-1o7.3-202
(1)
|
Ensembl | 795 nt | ||
| mRNA |
si:ch211-1o7.3-203
(1)
|
Ensembl | 829 nt | ||
| mRNA |
si:ch211-1o7.3-204
(1)
|
Ensembl | 556 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-1O7 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021477700 (1) | 1934 nt | ||
| Genomic | GenBank:CR457462 (1) | 166823 nt | ||
| Polypeptide | UniProtKB:F1R1Q1 (1) | 561 aa |
- Comparative Orthology
- Alliance
No data available
- Urasaki, A., Morishita, S., Naka, K., Uozumi, M., Abe, K., Huang, L., Watase, E., Nakagawa, O., Kawakami, K., Matsui, T., Bessho, Y., Inagaki, N. (2019) Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system. Scientific Reports. 9:12156
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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