Gene

afg3l1

ID
ZDB-GENE-121214-51
Name
AFG3-like AAA ATPase 1
Symbol
afg3l1 Nomenclature History
Previous Names
  • si:ch1073-174d20.2
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in mitochondrial protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be part of m-AAA complex.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa10560Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa44363Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa44364Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa44365Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With afg3l1 Human Ortholog
No data available
Associated With afg3l1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003960 ATPase, AAA-type, conserved site
Domain IPR000642 Peptidase M41
Domain IPR003593 AAA+ ATPase domain
Domain IPR003959 ATPase, AAA-type, core
Domain IPR011546 Peptidase M41, FtsH extracellular
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Domain Details Per Protein
Protein Length AAA ATPase, AAA+ lid domain AAA+ ATPase domain ATPase, AAA-type, conserved site ATPase, AAA-type, core ATP-dependent Zinc Metalloprotease ATP-dependent zinc metalloprotease, FtsH Peptidase M41 Peptidase M41, FtsH extracellular Peptidase M41-like P-loop containing nucleoside triphosphate hydrolase
UniProtKB:E7F6D6
InterPro
751
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:ch1073-174d20.2-201 (1)
Ensembl
Ensembl 3,979 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inFosmidCH1073-174D20ZFIN Curated Data
Contained inFosmidCH1073-415N3ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_005163207 (1)3228 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:FP245543 (1)33849 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:E7F6D6 (1)751 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Species Symbol Chromosome Accession # Evidence
MouseAfg3l18
Phylogenetic tree (1)
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
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