Gene

adgre5b.2

ID
ZDB-GENE-121214-277
Name
adhesion G protein-coupled receptor E5b, duplicate 2
Symbol
adgre5b.2 Nomenclature History
Previous Names
  • Cd97c (1)
  • si:ch73-221f6.6
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in vibratory urticaria. Is expressed in several structures, including eye; heart; integument; liver; and pleuroperitoneal region. Orthologous to several human genes including ADGRE5 (adhesion G protein-coupled receptor E5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Harty et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgre5b.2 Human Ortholog
No data available
Associated With adgre5b.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000203 GPS motif
Domain IPR017981 GPCR, family 2-like, 7TM
Family IPR000832 GPCR, family 2, secretin-like
Family IPR003056 GPCR, family 2, ADGRE2/ADGRE5
Homologous_superfamily IPR046338 GAIN domain superfamily
Domain Details Per Protein
Protein Length GAIN domain superfamily GPCR, family 2, ADGRE2/ADGRE5 GPCR, family 2-like, 7TM GPCR, family 2, secretin-like GPS motif
UniProtKB:R4GDT3 693
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA adgre5b.2-201 (1) Havana 2301 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations