Gene
pfkla
- ID
- ZDB-GENE-121207-1
- Name
- phosphofructokinase, liver a
- Symbol
- pfkla Nomenclature History
- Previous Names
-
- pfkl
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have 6-phosphofructokinase activity; ATP binding activity; and metal ion binding activity. Predicted to be involved in fructose 6-phosphate metabolic process and glycolytic process. Predicted to localize to cytoplasm. Orthologous to human PFKL (phosphofructokinase, liver type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Hemolytic anemia due to phosphofructokinase deficiency |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR015912 | Phosphofructokinase, conserved site |
| Domain | IPR000023 | Phosphofructokinase domain |
| Family | IPR009161 | ATP-dependent 6-phosphofructokinase, eukaryotic-type |
| Family | IPR022953 | ATP-dependent 6-phosphofructokinase |
| Family | IPR041914 | ATP-dependent 6-phosphofructokinase, vertebrate-type |
| Homologous_superfamily | IPR035966 | Phosphofructokinase superfamily |
Domain Details Per Protein
| Protein | Length | ATP-dependent 6-phosphofructokinase | ATP-dependent 6-phosphofructokinase, eukaryotic-type | ATP-dependent 6-phosphofructokinase, vertebrate-type | Phosphofructokinase, conserved site | Phosphofructokinase domain | Phosphofructokinase superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F9M6
|
780 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance