Gene
uba7
- ID
- ZDB-GENE-121120-4
- Name
- ubiquitin-like modifier activating enzyme 7
- Symbol
- uba7 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have ubiquitin activating enzyme activity. Predicted to be involved in cellular response to DNA damage stimulus; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm and nucleus. Orthologous to human UBA7 (ubiquitin like modifier activating enzyme 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033127 | Ubiquitin-activating enzyme E1, Cys active site |
| Conserved_site | IPR018074 | Ubiquitin-activating enzyme E1, conserved site |
| Domain | IPR000594 | THIF-type NAD/FAD binding fold |
| Domain | IPR018965 | Ubiquitin-activating enzyme E1, C-terminal |
| Domain | IPR019572 | Ubiquitin-activating enzyme, SCCH domain |
| Domain | IPR032418 | Ubiquitin-activating enzyme E1, FCCH domain |
| Domain | IPR032420 | Ubiquitin-activating enzyme E1, four-helix bundle |
| Family | IPR000011 | Ubiquitin/SUMO-activating enzyme E1-like |
| Family | IPR018075 | Ubiquitin-activating enzyme E1 |
| Family | IPR045886 | ThiF/MoeB/HesA family |
| Homologous_superfamily | IPR035985 | Ubiquitin-activating enzyme |
| Homologous_superfamily | IPR038252 | Ubiquitin-activating enzyme E1, C-terminal domain superfamily |
| Homologous_superfamily | IPR042063 | Ubiquitin-activating enzyme E1, SCCH domain |
| Homologous_superfamily | IPR042302 | Ubiquitin-activating enzyme E1, FCCH domain superfamily |
| Homologous_superfamily | IPR042449 | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 |
Domain Details Per Protein
| Protein | Length | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin-activating enzyme | Ubiquitin-activating enzyme E1 | Ubiquitin-activating enzyme E1, conserved site | Ubiquitin-activating enzyme E1, C-terminal | Ubiquitin-activating enzyme E1, C-terminal domain superfamily | Ubiquitin-activating enzyme E1, Cys active site | Ubiquitin-activating enzyme E1, FCCH domain | Ubiquitin-activating enzyme E1, FCCH domain superfamily | Ubiquitin-activating enzyme E1, four-helix bundle | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 | Ubiquitin-activating enzyme E1, SCCH domain | Ubiquitin-activating enzyme, SCCH domain | Ubiquitin/SUMO-activating enzyme E1-like |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7EYF3
|
1016 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance