Gene

muc5.1

ID

ZDB-GENE-120822-1

Name

mucin 5.1, oligomeric mucus/gel-forming

Symbol

muc5.1 Nomenclature History

Previous Names

muc5ac
muc5c (1)
muc5l
muc (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have peptidase inhibitor activity. Predicted to localize to extracellular region. Is expressed in esophagus; gill lamella; intestine; and pharynx.

Genome Resources

Note

This gene is orthologous to BOTH human MUC5AC and MUC5B (evidence: amino acid alignment, phylogenetic tree and synteny). The nomenclature has been updated to avoid implying an orthologous relationship to only one of these genes.

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With muc5.1 Human Ortholog

No data available

Associated With muc5.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001007	VWFC domain
Domain	IPR001846	von Willebrand factor, type D domain
Domain	IPR002919	Trypsin Inhibitor-like, cysteine rich domain
Domain	IPR006207	Cystine knot, C-terminal
Domain	IPR008037	Pacifastin domain
Domain	IPR014853	VWF/SSPO/Zonadhesin-like, cysteine-rich domain
Domain	IPR025155	WxxW domain
Homologous_superfamily	IPR036084	Serine protease inhibitor-like superfamily
Homologous_superfamily	IPR036201	Pacifastin domain superfamily

Domain Details Per Protein

Protein	Length	Cystine knot, C-terminal	Pacifastin domain	Pacifastin domain superfamily	Serine protease inhibitor-like superfamily	Trypsin Inhibitor-like, cysteine rich domain	von Willebrand factor, type D domain	VWFC domain	VWF/SSPO/Zonadhesin-like, cysteine-rich domain	WxxW domain
UniProtKB:A0A8M9PH65 InterPro	5120
UniProtKB:X1WBL9 InterPro	5282
UniProtKB:A0A8M9PN30 InterPro	4214

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	muc5.1-201 (1) Ensembl	Havana	16267 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations