Gene
map3k14a
- ID
- ZDB-GENE-120215-80
- Name
- mitogen-activated protein kinase kinase kinase 14a
- Symbol
- map3k14a Nomenclature History
- Previous Names
-
- si:dkey-260c8.4
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and JUN kinase kinase kinase activity. Predicted to be involved in MAPK cascade. Predicted to act upstream of or within protein phosphorylation. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MAP3K14 (mitogen-activated protein kinase kinase kinase 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 112 | Alliance | Immunodeficiency 112 | 620449 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Mitogen-activated protein kinase kinase kinase | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:E7FEY1
|
825 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map3k14a-201
(1)
|
Ensembl | 2,846 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance