ZFIN is now using GRCz12tu for Genomic Data
Gene
onecut2
- ID
- ZDB-GENE-120215-73
- Name
- one cut homeobox 2
- Symbol
- onecut2 Nomenclature History
- Previous Names
-
- si:ch1073-41k10.1
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in brain; retina; retinal ganglion cell layer; retinal inner plexiform layer; and retinal outer nuclear layer. Orthologous to human ONECUT2 (one cut homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Vassalli et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CUT domain | CUT Homeobox Domain-Containing Protein | Homedomain-like superfamily | Homeodomain | Lambda repressor-like, DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PU69 | InterPro | 407 | |||||
| UniProtKB:A0A8M1QUT6 | InterPro | 461 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
onecut2-201
(1)
|
Ensembl | 1,379 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers