Gene
arhgap44b
- ID
- ZDB-GENE-120206-2
- Name
- Rho GTPase activating protein 44b
- Symbol
- arhgap44b Nomenclature History
- Previous Names
-
- arhgap44
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of Rac protein signal transduction; regulation of actin cytoskeleton organization; and regulation of dendritic spine morphogenesis. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Predicted to be located in dendrite; presynapse; and recycling endosome. Predicted to be active in several cellular components, including dendritic spine; postsynaptic density; and presynaptic active zone. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and skin melanoma. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | BAR domain | Rho GTPase-activating protein 17/44/SH3BP1-like | Rho GTPase-activating protein domain | Rho GTPase activation protein |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PXE0 | InterPro | 859 | |||||
| UniProtKB:A0A8M9Q9A4 | InterPro | 856 | |||||
| UniProtKB:A0A8M9QF17 | InterPro | 729 | |||||
| UniProtKB:A0A8M9QJD4 | InterPro | 861 | |||||
| UniProtKB:A0A8M9QN54 | InterPro | 853 | |||||
| UniProtKB:A0A8M9QN52 | InterPro | 862 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arhgap44-201
(1)
|
Ensembl | 1,992 nt | ||
| mRNA |
arhgap44-202
(1)
|
Ensembl | 2,121 nt |
Interactions and Pathways
No data available
Plasmids
No data available