Gene

ank2a

ID

ZDB-GENE-111215-3

Name

ankyrin 2a, neuronal

Symbol

ank2a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ank2a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
ankyrin-B-related cardiac arrhythmia	Alliance	Cardiac arrhythmia, ankyrin-B-related	600919
ankyrin-B-related cardiac arrhythmia	Alliance	Long QT syndrome 4	600919

Associated With ank2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR000906	ZU5 domain
Domain	IPR040745	Ankyrin, UPA domain
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	Ankyrin, UPA domain	Death domain	Death-like domain superfamily	ZU5 domain
UniProtKB:E7F4G7 InterPro	3760
UniProtKB:A0A8M9QDJ9 InterPro	4856
UniProtKB:A0A8M9Q8A0 InterPro	4811
UniProtKB:A0A8M9PJS2 InterPro	2934
UniProtKB:A0A8M9PJQ6 InterPro	4850
UniProtKB:A0A8M9Q2Z7 InterPro	4823
UniProtKB:A0A8M9Q0B4 InterPro	598
UniProtKB:A0A8M9QDL1 InterPro	4838
UniProtKB:A0A8M9P7S7 InterPro	593
UniProtKB:A0A8M9Q892 InterPro	4835
UniProtKB:A0A8M9PX61 InterPro	4826
UniProtKB:A0A8M9Q2X9 InterPro	4844
UniProtKB:A0A8M9PIM6 InterPro	588
UniProtKB:A0A8M9PX50 InterPro	4855
UniProtKB:A0A8M9PX04 InterPro	596
UniProtKB:A0A8M9PPL1 InterPro	599
UniProtKB:A0A8M9QDL7 InterPro	4823
UniProtKB:A0A8M9PX68 InterPro	4777
UniProtKB:A0A8M9QDM2 InterPro	3861
UniProtKB:A0A8M9QDK6 InterPro	4853

Transcripts

Genome Browsers

NCBI

No data available

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations