Gene
klf4
- ID
- ZDB-GENE-111014-1
- Name
- Kruppel like factor 4
- Symbol
- klf4 Nomenclature History
- Previous Names
-
- klf4a
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of cell population proliferation and stem cell proliferation. Predicted to be located in nucleus. Is expressed in several structures, including EVL; digestive system; ectoderm; heart; and nervous system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human KLF4 (KLF transcription factor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 17 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
| UniProtKB:A9X6Q5 | InterPro | 396 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids