Gene

tlcd3bb

ID
ZDB-GENE-110603-2
Name
TLC domain containing 3Bb
Symbol
tlcd3bb Nomenclature History
Previous Names
  • fam57bb
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable sphingosine N-acyltransferase activity. Acts upstream of or within regulation of lipid metabolic process; regulation of synapse organization; and startle response. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in cone-rod dystrophy 22. Orthologous to human TLCD3B (TLC domain containing 3B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa35187Allele with one point mutationUnknownSplice SiteENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
zf3799Allele with one deletionUnknownUnknownCRISPR
1 - 2 of 2
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-tlcd3bbTomasello et al., 2021
1 - 1 of 1
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Human Disease
Associated With tlcd3bb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cone-rod dystrophy 22 Alliance Cone-rod dystrophy 22 619531
1 - 1 of 1
Associated With tlcd3bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006634 TRAM/LAG1/CLN8 homology domain
Family IPR050846 TLC domain-containing
1 - 2 of 2
Domain Details Per Protein
Protein Length TLC domain-containing TRAM/LAG1/CLN8 homology domain
UniProtKB:E7FG14
InterPro
295
UniProtKB:A0A8M2B2L9
InterPro
193
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 12
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fam57bb-202 (1)
Ensembl
Ensembl 1,374 nt
ZFIN BLAST
mRNA tlcd3bb-201 (1)
Ensembl
Ensembl 888 nt
ZFIN BLAST
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-166G5ZFIN Curated Data
1 - 1 of 1
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_001918931 (1)7880 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CR762399 (1)121539 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:E7FG14 (1)295 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTLCD3B16
Conserved genome location (synteny) (2)
Amino acid sequence comparison (1)
MouseTlcd3b7
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
TSV
1 - 3 of 3
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