ZFIN is now using GRCz12tu for Genomic Data
Gene
avpr2ab
- ID
- ZDB-GENE-110411-48
- Name
- arginine vasopressin receptor 2a, duplicate b
- Symbol
- avpr2ab Nomenclature History
- Previous Names
-
- V2A(1) (1)
- si:ch211-272p8.4
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable vasopressin receptor activity. Predicted to be involved in several processes, including cellular response to hormone stimulus; positive regulation of cytosolic calcium ion concentration; and positive regulation of vasoconstriction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; male organism; and testis. Human ortholog(s) of this gene implicated in X-linked nephrogenic diabetes insipidus; nephrogenic diabetes insipidus; and nephrogenic syndrome of inappropriate antidiuresis. Orthologous to human AVPR2 (arginine vasopressin receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| nephrogenic syndrome of inappropriate antidiuresis | Alliance | Nephrogenic syndrome of inappropriate antidiuresis | 300539 |
| X-linked nephrogenic diabetes insipidus | Alliance | Diabetes insipidus, nephrogenic, 1 | 304800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Vasopressin receptor |
|---|---|---|---|---|---|
| UniProtKB:A0A8M1QV55 | InterPro | 542 | |||
| UniProtKB:A0AB32THR6 | InterPro | 447 | |||
| UniProtKB:A0AC58IKX9 | InterPro | 539 | |||
| UniProtKB:A0AC58IL09 | InterPro | 444 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
avpr2ab-201
(1)
|
Ensembl | 1,323 nt | ||
| mRNA |
avpr2ab-202
(1)
|
Ensembl | 1,306 nt | ||
| mRNA |
avpr2ab-203
(1)
|
Ensembl | 1,014 nt | ||
| mRNA |
avpr2ab-204
(1)
|
Ensembl | 1,326 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers