Gene
ppm1ka
- ID
- ZDB-GENE-110411-37
- Name
- protein phosphatase, Mg2+/Mn2+ dependent 1Ka
- Symbol
- ppm1ka Nomenclature History
- Previous Names
-
- si:ch211-149b19.3
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in regulation of intracellular signal transduction. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human PPM1K (protein phosphatase, Mg2+/Mn2+ dependent 1K).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| maple syrup urine disease | Alliance | Maple syrup urine disease, mild variant | 615135 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PPM-type phosphatase, divalent cation binding | PPM-type phosphatase-like domain | PPM-type phosphatase-like domain superfamily | Protein phosphatase 2C |
|---|---|---|---|---|---|
|
UniProtKB:E7FAZ1
|
358 | ||||
|
UniProtKB:A0A8M3B6G2
|
370 | ||||
|
UniProtKB:A0A8M9P5N7
|
290 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
si:ch211-149b19.3-203
(1)
|
Ensembl | 1,592 nt | ||
| mRNA |
ppm1k-203
(1)
|
Ensembl | 3,708 nt | ||
| mRNA |
si:ch211-149b19.3-202
(1)
|
Ensembl | 1,392 nt |
Interactions and Pathways
No data available
Plasmids
No data available