Gene
nup214
- ID
- ZDB-GENE-110203-3
- Name
- nucleoporin 214
- Symbol
- nup214 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have nuclear localization sequence binding activity. Predicted to be involved in RNA export from nucleus and protein import into nucleus. Predicted to localize to nuclear pore. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Orthologous to human NUP214 (nucleoporin 214).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kindermann et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kindermann et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| acute lymphoblastic leukemia | Alliance | Leukemia, T-cell acute lymphoblastic, somatic | 613065 |
| acute myeloid leukemia | Alliance | Leukemia, acute myeloid, somatic | 601626 |
| {Encephalopathy, acute, infection-induced, susceptibility to, 9} | 618426 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Nuclear pore complex protein | Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain | WD40 repeat | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z6M9
|
2055 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available