Gene
pds5b
- ID
- ZDB-GENE-091217-2
- Name
- PDS5 cohesin associated factor B
- Symbol
- pds5b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to be involved in DNA repair and mitotic sister chromatid cohesion. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including cranium; digestive system; nervous system; optic cup; and otic vesicle. Orthologous to human PDS5B (PDS5 cohesin associated factor B).
- Genome Resources
- Note
-
Represented by LOC565592 and ENSDARG00000061312 on LG15 in Zv8.
- Comparative Information
-
- All Expression Data
- 3 figures from Mönnich et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-pds5b | N/A | Huang et al., 2013 |
| TALEN1-pds5b | Thomas et al., 2014 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Armadillo-like helical | Armadillo-type fold | AT hook, DNA-binding motif | Sister chromatid cohesion protein Pds5 |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IP12 | InterPro | 1408 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-360F20 | ZFIN Curated Data | |
| Contained in | BAC | CH211-250I4 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-26O16 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_688861 (1) | 5330 nt | ||
| Genomic | GenBank:CT027778 (1) | 160888 nt | ||
| Polypeptide | UniProtKB:A0A0R4IP12 (1) | 1408 aa |
- Gao, S., Liu, S., Yao, J., Li, N., Yuan, Z., Zhou, T., Li, Q., Liu, Z. (2017) Genomic organization and evolution of olfactory receptors and trace amine-associated receptors in channel catfish, Ictalurus punctatus. Biochimica et biophysica acta. 1861(3):644-651
- Thomas, H.R., Percival, S.M., Yoder, B.K., Parant, J.M. (2014) High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis. PLoS One. 9:e114632
- Huang, H.T., Kathrein, K.L., Barton, A., Gitlin, Z., Huang, Y.H., Ward, T.P., Hofmann, O., Dibiase, A., Song, A., Tyekucheva, S., Hide, W., Zhou, Y., and Zon, L.I. (2013) A network of epigenetic regulators guides developmental haematopoiesis in vivo. Nature cell biology. 15(12):1516-1525
- Mönnich, M., Banks, S., Eccles, M., Dickinson, E., and Horsfield, J. (2009) Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin. Gene expression patterns : GEP. 9(8):586-594
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