ZFIN is now using GRCz12tu for Genomic Data
Gene
sh3bp2
- ID
- ZDB-GENE-091204-268
- Name
- SH3-domain binding protein 2
- Symbol
- sh3bp2 Nomenclature History
- Previous Names
-
- si:ch211-241o7.3
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable SH3 domain binding activity. Predicted to be involved in signal transduction. Human ortholog(s) of this gene implicated in cherubism 1. Orthologous to human SH3BP2 (SH3 domain binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cherubism 1 | Alliance | Cherubism | 118400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | PH-like domain superfamily | Pleckstrin homology domain | SH2 domain | SH2 domain superfamily | SH3 domain-binding protein 2 |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z301 | InterPro | 542 | |||||
| UniProtKB:A0A8M2B1N9 | InterPro | 543 | |||||
| UniProtKB:A0A8M2B234 | InterPro | 532 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sh3bp2-201
(1)
|
Ensembl | 1,485 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers