ZFIN is now using GRCz12tu for Genomic Data
Gene
map3k15
- ID
- ZDB-GENE-091204-246
- Name
- mitogen-activated protein kinase kinase kinase 15
- Symbol
- map3k15 Nomenclature History
- Previous Names
-
- si:dkey-108d10.2
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in JNK cascade and p38MAPK cascade. Is expressed in pancreatic D cell; posterior pancreatic bud; and pronephric glomerulus. Orthologous to human MAP3K15 (mitogen-activated protein kinase kinase kinase 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Tarifeño-Saldivia et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR025136 | MAP3K, TRAFs-binding domain |
| Domain | IPR043969 | MAP3K, PH domain |
| Domain | IPR046872 | MAP3K, deoxyribohydrolase domain |
| Domain | IPR046873 | MAP3K, HisK-N-like globin domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | MAP3K, deoxyribohydrolase domain | MAP3K, HisK-N-like globin domain | MAP3K, PH domain | MAP3K, TRAFs-binding domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Sterile alpha motif/pointed domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PX79 | InterPro | 1358 | |||||||||
| UniProtKB:A0A8M9PR29 | InterPro | 1303 | |||||||||
| UniProtKB:A0A8M9Q877 | InterPro | 1335 | |||||||||
| UniProtKB:A0A8M9PEA4 | InterPro | 1361 | |||||||||
| UniProtKB:A0A8M9PEA8 | InterPro | 1008 | |||||||||
| UniProtKB:A0A8M9PXZ5 | InterPro | 1360 | |||||||||
| UniProtKB:A0A8M3B6Q7 | InterPro | 1332 | |||||||||
| UniProtKB:A0AB32TD52 | InterPro | 1357 | |||||||||
| UniProtKB:A0AB32TMB0 | InterPro | 1300 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map3k15-201
(1)
|
Ensembl | 6,943 nt | ||
| mRNA |
map3k15-202
(1)
|
Ensembl | 4,658 nt | ||
| mRNA |
map3k15-203
(1)
|
Ensembl | 4,047 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers