Gene
pld1b
- ID
- ZDB-GENE-070510-3
- Name
- phospholipase D1b
- Symbol
- pld1b Nomenclature History
- Previous Names
-
- si:dkey-83f6.3
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have N-acylphosphatidylethanolamine-specific phospholipase D activity; phosphatidylinositol binding activity; and phospholipase D activity. Predicted to be involved in cell motility. Predicted to localize to Golgi apparatus. Human ortholog(s) of this gene implicated in developmental cardiac valvular defect. Orthologous to human PLD1 (phospholipase D1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Busch-Nentwich et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental cardiac valvular defect | Alliance | Cardiac valvular dysplasia 1 | 212093 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001683 | Phox homology |
| Domain | IPR001736 | Phospholipase D/Transphosphatidylase |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR025202 | Phospholipase D-like domain |
| Family | IPR015679 | Phospholipase D family |
| Family | IPR016555 | Phospholipase D, eukaryotic type |
| Homologous_superfamily | IPR036871 | PX domain superfamily |
Domain Details Per Protein
| Protein | Length | Phospholipase D, eukaryotic type | Phospholipase D family | Phospholipase D-like domain | Phospholipase D/Transphosphatidylase | Phox homology | Pleckstrin homology domain | PX domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PGG2
|
1042 |
Interactions and Pathways
No data available
Plasmids
No data available