Gene

lrfn4a

ID

ZDB-GENE-091113-56

Name

leucine rich repeat and fibronectin type III domain containing 4a

Symbol

lrfn4a Nomenclature History

Previous Names

si:ch211-250a23.3

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to be involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Predicted to localize to cell surface; glutamatergic synapse; and integral component of postsynaptic density membrane. Orthologous to human LRFN4 (leucine rich repeat and fibronectin type III domain containing 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With lrfn4a Human Ortholog

No data available

Associated With lrfn4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000483	Cysteine-rich flanking region, C-terminal
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013098	Immunoglobulin I-set
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR032675	Leucine-rich repeat domain superfamily
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Repeat	IPR001611	Leucine-rich repeat
Repeat	IPR003591	Leucine-rich repeat, typical subtype

Domain Details Per Protein

Protein	Length	Cysteine-rich flanking region, C-terminal	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin I-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype	Immunoglobulin subtype 2	Leucine-rich repeat	Leucine-rich repeat domain superfamily	Leucine-rich repeat, typical subtype
UniProtKB:E9QF02 InterPro	892

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	lrfn4a-201 (1) Ensembl	Havana	3096 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	lrfn4a-002 (1) Ensembl	Havana	499 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations