ZFIN is now using GRCz12tu for Genomic Data
Gene
yme1l1a
- ID
- ZDB-GENE-091113-41
- Name
- YME1-like 1a
- Symbol
- yme1l1a Nomenclature History
- Previous Names
-
- si:dkey-229j15.3
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable ATP binding activity; ATP hydrolysis activity; and peptidase activity. Predicted to be involved in anatomical structure morphogenesis; mitochondrial protein processing; and positive regulation of mitochondrial fusion. Predicted to be located in mitochondrial membrane. Human ortholog(s) of this gene implicated in optic atrophy 11. Orthologous to human YME1L1 (YME1 like 1 ATPase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| optic atrophy 11 | Alliance | ?Optic atrophy 11 | 617302 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003960 | ATPase, AAA-type, conserved site |
| Domain | IPR000642 | Peptidase M41 |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Domain | IPR041569 | AAA ATPase, AAA+ lid domain |
| Family | IPR005936 | ATP-dependent zinc metalloprotease, FtsH |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR037219 | Peptidase M41-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA ATPase, AAA+ lid domain | AAA+ ATPase domain | ATPase, AAA-type, conserved site | ATPase, AAA-type, core | ATP-dependent zinc metalloprotease, FtsH | Peptidase M41 | Peptidase M41-like | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7EZJ5 | InterPro | 729 | ||||||||
| UniProtKB:A0A8M1RL79 | InterPro | 721 | ||||||||
| UniProtKB:A0ACD6B5E4 | InterPro | 729 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
yme1l1a-201
(1)
|
Ensembl | 2,190 nt | ||
| mRNA |
yme1l1a-202
(1)
|
Ensembl | 3,017 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers